Tissera Names Sir Roy York Calne, Reputed Surgeon and Transplantation Expert, to Scientific Advisory Board

TEL AVIV, Israel - April 22, 2004 - Tissera, Inc. (OTCBB:TSSR), a biotechnology company dedicated to the development and commercialization of tissue transplantation therapies utilizing novel tissue precursor regeneration technologies for the treatment of disease and organ transplantation, has appointed Roy York Calne, M.D., to the company’s Scientific Advisory Board. Sir Roy Calne, who was granted the Knight Bachelor Honors in 1986, is a revered professor, author and surgeon in the field of transplantation surgery.

Currently Emeritus Professor of Surgery at the University of Cambridge and General Surgeon and Consultant in Transplantation Surgery, Dr. Calne is also Professor of Surgery at the National University of Singapore. Among his many previous appointments, he served as an active Professor of Surgery at the University of Cambridge for many years, as well as the Senior Vice President of the Royal College of Surgeons of England. Since the publication of his first book, Renal Transplantation, in 1963, Dr. Calne has published over 18 books, hundreds of articles, and lectured at some of the world’s most admired medical schools including Harvard University, University of Cambridge, University of London, and  Oxford  University .

“It is an honor to have one of the great minds in transplantation medicine join our Scientific Advisory Board,” said Vicki Rabenou, CEO of Tissera. “Dr. Calne has been a pioneer in the field since 1959, when he engaged in organ transplantation research and described the first effective immunosuppressive treatment for kidney transplantation. He   started the Cambridge Kidney Transplant Program in 1965, and the first European Liver Transplant Program in the late 60’s. He brings more than 40 years of insight, research and hands-on experience to our Board.”

Dr. Calne is also acclaimed for being the first surgeon to perform a pancreas transplant in the United Kingdom in 1979 and the first to perform an intestinal transplant there in 1992. Former President of the International Transplantation Society, Dr. Calne has been awarded numerous distinctions and honorary degrees in many countries and prestigious academic institutions around the world for his groundbreaking work in medicine.